As you are today, and always, in my thoughts and loved. Happy Birthday, Gimmie.
Showing posts with label cats. Show all posts
Showing posts with label cats. Show all posts
07 April 2011
12 July 2010
HCM Clinic - Birmingham, AL
Anyone wishing to participate in an HCM clinic at Pet Cardiologist, in Birmingham, AL may contact me for inclusion at:
gimmiesfishes@gmail.com
Date: 14 August - pending
gimmiesfishes@gmail.com
Date: 14 August - pending
18 May 2010
29 April 2010
01 February 2010
Teva Animal Health, Inc. expands nationwide ketamine recall
Date: January 14, 2010
On December 22, 2009, the U.S. Food and Drug Administration (FDA) announced a nationwide voluntary recall of ketamine hydrochloride injectable (100mg/ml, 10 ml vials) manufactured by Teva Animal Health, Inc. Not all Teva products are affected by the recall. Teva Animal Health also manufactures ketamine hydrochloride products for other companies. These products are sold under various brand names and can include the following:
AmTech Group, Inc. (Ketamine Hydrochloride Injection, USP)
Butler (KetaThesia)
LLOYD Laboratories (VetaKet)
Phoenix (Ketaject)
RXV (Keta-Sthetic)
VEDCO (KetaVed)
Fort Dodge/Pfizer (Ketaset)
Teva Animal Health does not distribute products internationally.
Teva Animal Health is not the only manufacturer of ketamine hydrochloride in the U.S. and not all products sold under the above-listed names listed are affected. Therefore, regardless of the brand name on the product, look at the lot number on all ketamine hydrochloride (100 mg/ml in 10 ml vials) products.
If the lot number is 6 numeric digits, the product is NOT part of the recall
If the lot number is 7 numeric digits, the product should be returned
If the lot number starts with "5401", regardless of the number of digits or the presence of letters in the lot code, the product should be returned
Veterinarians with questions may contact Teva Animal Health at 800-759-3664 from 8:00 am – 5:00 pm (CST) Monday through Friday.
http://www.fda.gov/Safety/Recalls/ucm195118.htm
FOR IMMEDIATE RELEASE -- December 21, 2009 - Teva Animal Health, Inc. is expanding a nationwide voluntary recall of Ketamine Hydrochloride Injection, USP CIII 100mg/mL in 10mL vials for all lot numbers within their expiration dates to the Veterinary Level. This product had previously been recalled to the distributor level and is being expanded as a result of an increased trend in serious adverse events associated with this product.
Veterinarians who have this product in their possession are instructed to cease using the product immediately and return it to their distributor.
Ketamine Hydrochloride is a rapid acting, non-narcotic, non-barbiturate agent for anesthetic use in cats and for restraint in subhuman primates. This recall is being conducted as a result of an increased trend in serious adverse events associated with this product, including lack of effect, prolonged effect, and death and involves all lot numbers within expiration.
Teva Animal Health, Inc is voluntarily recalling the aforementioned product. The FDA has been apprised of this action.
Consumers with questions may contact 800-759-3664 from 8:00am – 5:00pm CST Monday-Friday.
On December 22, 2009, the U.S. Food and Drug Administration (FDA) announced a nationwide voluntary recall of ketamine hydrochloride injectable (100mg/ml, 10 ml vials) manufactured by Teva Animal Health, Inc. Not all Teva products are affected by the recall. Teva Animal Health also manufactures ketamine hydrochloride products for other companies. These products are sold under various brand names and can include the following:
AmTech Group, Inc. (Ketamine Hydrochloride Injection, USP)
Butler (KetaThesia)
LLOYD Laboratories (VetaKet)
Phoenix (Ketaject)
RXV (Keta-Sthetic)
VEDCO (KetaVed)
Fort Dodge/Pfizer (Ketaset)
Teva Animal Health does not distribute products internationally.
Teva Animal Health is not the only manufacturer of ketamine hydrochloride in the U.S. and not all products sold under the above-listed names listed are affected. Therefore, regardless of the brand name on the product, look at the lot number on all ketamine hydrochloride (100 mg/ml in 10 ml vials) products.
If the lot number is 6 numeric digits, the product is NOT part of the recall
If the lot number is 7 numeric digits, the product should be returned
If the lot number starts with "5401", regardless of the number of digits or the presence of letters in the lot code, the product should be returned
Veterinarians with questions may contact Teva Animal Health at 800-759-3664 from 8:00 am – 5:00 pm (CST) Monday through Friday.
http://www.fda.gov/Safety/Recalls/ucm195118.htm
FOR IMMEDIATE RELEASE -- December 21, 2009 - Teva Animal Health, Inc. is expanding a nationwide voluntary recall of Ketamine Hydrochloride Injection, USP CIII 100mg/mL in 10mL vials for all lot numbers within their expiration dates to the Veterinary Level. This product had previously been recalled to the distributor level and is being expanded as a result of an increased trend in serious adverse events associated with this product.
Veterinarians who have this product in their possession are instructed to cease using the product immediately and return it to their distributor.
Ketamine Hydrochloride is a rapid acting, non-narcotic, non-barbiturate agent for anesthetic use in cats and for restraint in subhuman primates. This recall is being conducted as a result of an increased trend in serious adverse events associated with this product, including lack of effect, prolonged effect, and death and involves all lot numbers within expiration.
Teva Animal Health, Inc is voluntarily recalling the aforementioned product. The FDA has been apprised of this action.
Consumers with questions may contact 800-759-3664 from 8:00am – 5:00pm CST Monday-Friday.
07 January 2010
Thinking about you today, my love...
You're on my mind and in my heart, my darling little boy. If you only knew how many people and SX have been touched by your story.
I love you Gimmie.
I am including a photo of you, with your brother, Bilbo, and new sibblings PR Junipurr Lily, GP Rose, and new little brother GoNaked FreudianSlip of RmplSlkSknz, aka, "Siggy". You'll always remain a forever part of our family... we miss you, Gims.
In back: Gimli, aka "Gimmie Gims", and L-R:
Siggy, Rose, Lily, and in front, Bilbo - Gimli's cattery mate.
The cattery name is ours - and my husband came up with it.
We do not breed. The name is strictly a vanity.
08 April 2009
Remembering Gimli on the Anniversary of his Death
I woke up this morning not intending to dwell, but the memories of last year - on this day - came flooding back fresh and raw. As I lay in bed trying to wake up, reflect on my feelings, and try to move past them, Bilbo (Godz Bilbo Bombadil - our 4 year old cream point & white Sphynx boy, and Gimli's litter mate) came bounding upon the bed, pawed me on the head (so I would raise up the cover), climbed inside and into my arms, settled comfortably, and began to purr. He was followed closely by his own little shadow, Rosie (PR Godz Rose of Sharron - our 16 month old dilute calico girl who is Gimli's niece).
Both nestled warmly against me and - unbeknownst to them - gave me exactly the kind of comfort that I needed more than anything in the world. Rose's sister, Lily, (PR Godz Junipurr Lily - our 16 month old red & white girl who is also Gimli's niece) tentatively came to see where Bilbo and Rose had gone and, after allowing me to hug her without squirming away (she's a daddy's girl wholeheartedly) she settled into a warm spot by her two favorite non-humans.
I wondered, this morning, if Gimmie would've liked the girls, especially since Rose is so much like him.
I wonder if he'd be pissy over the way Bilbo now tries to take his place (I'm betting yes on that one). I love these sweet little creatures so very much. They're all different and very loving, but there's a part of my heart that will always be Gimli's - my special boy.
Our loss was not forgotten by friends today or yesterday. In fact, over the last several weeks, and inparticularly right after the SBEN's issue #2 was released - where my story along with an issue dedication to Gimmie offered others a chance to remember with me - I have had numerous emails from all over the States, Europe and Africa. So many kind souls who deeply understand this sort of pain, loss, and love... and some, like myself, who have experienced unnecessary loss through the ignorance or apathy of a trusted vet.
This past weekend my husband and I attended a CFA show where Lily was shown in Open Premiership and Rose, already a Premier, worked on her Grand points. Bilbo was along as their moral support. I was benched by a Sphynx breeder that I know from online and from seeing at shows. He brought two little kittens to show and we had time, during the lulls, to talk about many things "Sphynx". I mentioned today's upcoming "anniversary" and how I was still angry about the use of Ketamine by the vet. He told me that he'd had two Sphynx (whole cats used in his breeding program) that were killed due to Ketamine use. One was pregnant and needed to have a C-section to deliver. She was given Ketamine and it killed her, along with all her kittens. He had her necropsied and the pathologist declined to say the cause was Ketamine although all signs pointed that way. Another of his cats had a medical issue and the same vet needed to put it under and gave it ... guess what... Ketamine. It also died, was necropsied. The pathology report stated that its heart was enlarged (pointing to HCM), but it was enlarged, not from the disease, but from a "chemical". This cat was a particularly beloved cat and we both shared our vivid, unforgetable memories of having to place these loves in our refrigerators and ice chests as we prepared to go, or were enroute, to a pathology lab.
Like us, he also changed vets and banned the use of Ketamine on his cats... and like us, he experienced an apathetic response from his vet in regards to the deaths.
At the show this breeder sold one of the little kittens he had brought to a very nice looking couple. I heard him tell them that he would have the kitten spayed but that he did not use Ket/Val and did not want it to be used on the kitten in future. He said that he included instructions on anesthesias in the adoptive parents Take-Home kit. How I wish the breeder we used had either known, or advised us that way.
I have to hope that these horrible experiences that some of us have shared though the ignorant and unnecessary loss of life will help someone else, some other beloved Sphynx, and most certainly our own. Never again will what happened to Gimli happen to any of my cats. I can be grateful for that, at least.
So, on this sad anniversary date of my Gimmie's death I dedicate my day to happy memories of this incredible, wonderfully loving and beguiling little Sphynx boy.
From my friend, Jeanette, in South Africa:
Just so you know I have never forgotten you, altho I post very very seldom... I have several photos of Gimli, since you started posting them and he is also stuck in my mind. He was a special special baby and I feel your pain....across the ocean! You stay strong!!!!! and know your angel boy is with God..and in God's hands he is safe and loved, and he will be waiting at the gates of heaven, to welcome his mother home!!! He will never be forgotten as far as South Africa.
Thank you to all who have written and remembered my sadness and loss this day, this month, this year. I am proud to be a member of such a loving community, especially proud to be a part of the Sphynx community. Special cats, special people.
07 April 2009
Memories of Things Much Treasured Still
No new spongy balls, no special treats.
No hugs or kisses, no standing on mommy's feet.
No chirping at the birds, no watching down the street.
No happy little boy, so proud, so cute, so sweet.
What's left but memories of things much treasured still.
What's left but fighting to prohibit this drug that kills.
Happy, Would've-Been, 4th Birthday, Gimmie. We miss you sweet boy.
Thank you Dr. Kelly Kirkpatrick for destroying this life so needlessly and with the enormous lack of remorse or ethics that you displayed.
No hugs or kisses, no standing on mommy's feet.
No chirping at the birds, no watching down the street.
No happy little boy, so proud, so cute, so sweet.
What's left but memories of things much treasured still.
What's left but fighting to prohibit this drug that kills.
Happy, Would've-Been, 4th Birthday, Gimmie. We miss you sweet boy.
Thank you Dr. Kelly Kirkpatrick for destroying this life so needlessly and with the enormous lack of remorse or ethics that you displayed.
28 March 2009
April/May SBEN Issue - this issue is dedicated to Godz Gimli Gil-Galad
Volumn 1, Issue 2 - Sphynx Breeder / Enthusiast Newsletter
April/May 2009
- Read the article, Gimmie's Fishes, by this blog's author
08 February 2009
View the March/April Sphynx Breeders / Enthusiast Newsletter - and tell your friends
The information in the newsletter would be helpful and enjoyable to most owners / breeders of cats in the exotics line. In fact, a representative from the Devon Rex Society has already requested that an article on Nebulizing be reprinted in their own newsletter.
The entire cat fancy can benefit from the SBEN - but most profoundly benefited are Sphynx and other exotics.
Here's a direct link. Click on the image to download the PDF.
Thank you for reading this blog and the SBEN newsletter!
07 February 2009
A Willingness to Help... A Voice Being Heard
I often wonder if anyone, anywhere has truly been touched by my outcry over Ket/Val and our breed. It is something that I wonder about from time to time and especially as I continue to find myself staying up well into the early morning hours plugging away at this cause.
Just last week a supporter and friend of mine reminded me, quite accurately, that medicine is an art.
She very wisely said that, "Living beings are very complicated and there is no ONE recipe for success. And people are human and mistakes are made. I've learned to accept that over time. And that acceptance came with lots of tears, for sure. But reality is reality. And there is so much we can't prevent no matter how hard we try. Fighting that truth takes up a great deal of energy and the end result doesn't usually change much."
*sigh* Yes. I do agree with that assessment of the medical arts and our hearts; but let me share with you my reply.
"There is certainly much truth in your statement and I know you mean well to share it with me. However I can't let the Ketamine issue drop. I sorely wish I could as my life, my free-time, and my mental health would surely find relief.
My life has gone from being somewhat joyful to somewhat depressed and I find I am uplifted and encouraged as I in push onward with my little quest. I agree and I'm afraid, as you've eloquently stated, that all my efforts will be in vain in the long run ...BUT... if we don't TRY then we have to deal with complacency, apathy, indifference and, ultimately, more loss. I just don't want to do that.
So my plan right now is to continue bashing my head against the forces that be... a lack of vet knowledge, much indifference by the vet community, and a great possibility that I'll never really make a dent. But I'm trying, and at some point in time, perhaps I can stop and say... well, I gave it my best and I feel good about that.
Maybe it is a teeny bit different when we are owners and not breeders. Breeders see a great many babies go in and out of their life. Some share time at other catteries, some go to new homes, and some go to the great beyond. I realize attachments are made with each and every one, but due to the cycle of life and, sometimes death, that breeders witness there may be an adjustment that gives you all a better perspective.
For me and my husband, having two Sphynx was not something we would normally be able to afford but Fate saw a way to put our first two firmly in our hearts. Losing one so quickly and after such a commitment of our time and emotion has been tough and, for me at least, I've not found the solace in another little one that quenches the hurt and the missing.
I do appreciate your words and I know I have support among many here and w/in the Sphynx community. I also know that my intentions may be somewhat naive - but they're honest and I have to honour them."
Another supporter and friend wrote:
"Please don't forget: thanks to you, I (and I am just one or many!) know about the danger of Ketamine, and that means that my vet knows. This means that my Sphynx will not share Gimli's fate (I'm not sure if I am spelling his name correctly, so please let me know), nor will my Devon Rex, another breed that should not be given Ketamine. It also means that my vet has been alerted to this situation and will never give any other Sphynx or Devon Rex Ketamine. I hope he will alert other vets in Basel and even other Swiss vets. I have let Victoria in Austria know, so her Sphynx should also be safe from this scourge. We can also tell the whole Sphynx Friends group, and I think that it is indeed possible for ONE voice to make a huge difference! Look at articles in magazines that feature some person who has changed everything for a whole society or country or whatever! I very much admire you for not giving up on your "quest." Just don't listen to anybody who discourages you.
I also agree that medicine is an art. And, as my dad once pointed out to me: doctors practice medicine! And although practice makes perfect, perfect doesn't exist in art."
This week alone I was contacted by two people - from two different countries, both asking if I would kindly send the information I have on Ket/Val, and Gimli's story, to them. They both wanted to read the infomration and print it out for their vets. That makes me feel purposeful and proud.
As I am now being head-butted by Gimli's brother, Bilbo Bombadil, I must cease my ponderings for today and find something for this boy to nosh on.
Just last week a supporter and friend of mine reminded me, quite accurately, that medicine is an art.
She very wisely said that, "Living beings are very complicated and there is no ONE recipe for success. And people are human and mistakes are made. I've learned to accept that over time. And that acceptance came with lots of tears, for sure. But reality is reality. And there is so much we can't prevent no matter how hard we try. Fighting that truth takes up a great deal of energy and the end result doesn't usually change much."
*sigh* Yes. I do agree with that assessment of the medical arts and our hearts; but let me share with you my reply.
"There is certainly much truth in your statement and I know you mean well to share it with me. However I can't let the Ketamine issue drop. I sorely wish I could as my life, my free-time, and my mental health would surely find relief.
My life has gone from being somewhat joyful to somewhat depressed and I find I am uplifted and encouraged as I in push onward with my little quest. I agree and I'm afraid, as you've eloquently stated, that all my efforts will be in vain in the long run ...BUT... if we don't TRY then we have to deal with complacency, apathy, indifference and, ultimately, more loss. I just don't want to do that.
So my plan right now is to continue bashing my head against the forces that be... a lack of vet knowledge, much indifference by the vet community, and a great possibility that I'll never really make a dent. But I'm trying, and at some point in time, perhaps I can stop and say... well, I gave it my best and I feel good about that.
Maybe it is a teeny bit different when we are owners and not breeders. Breeders see a great many babies go in and out of their life. Some share time at other catteries, some go to new homes, and some go to the great beyond. I realize attachments are made with each and every one, but due to the cycle of life and, sometimes death, that breeders witness there may be an adjustment that gives you all a better perspective.
For me and my husband, having two Sphynx was not something we would normally be able to afford but Fate saw a way to put our first two firmly in our hearts. Losing one so quickly and after such a commitment of our time and emotion has been tough and, for me at least, I've not found the solace in another little one that quenches the hurt and the missing.
I do appreciate your words and I know I have support among many here and w/in the Sphynx community. I also know that my intentions may be somewhat naive - but they're honest and I have to honour them."
Another supporter and friend wrote:
"Please don't forget: thanks to you, I (and I am just one or many!) know about the danger of Ketamine, and that means that my vet knows. This means that my Sphynx will not share Gimli's fate (I'm not sure if I am spelling his name correctly, so please let me know), nor will my Devon Rex, another breed that should not be given Ketamine. It also means that my vet has been alerted to this situation and will never give any other Sphynx or Devon Rex Ketamine. I hope he will alert other vets in Basel and even other Swiss vets. I have let Victoria in Austria know, so her Sphynx should also be safe from this scourge. We can also tell the whole Sphynx Friends group, and I think that it is indeed possible for ONE voice to make a huge difference! Look at articles in magazines that feature some person who has changed everything for a whole society or country or whatever! I very much admire you for not giving up on your "quest." Just don't listen to anybody who discourages you.
I also agree that medicine is an art. And, as my dad once pointed out to me: doctors practice medicine! And although practice makes perfect, perfect doesn't exist in art."
This week alone I was contacted by two people - from two different countries, both asking if I would kindly send the information I have on Ket/Val, and Gimli's story, to them. They both wanted to read the infomration and print it out for their vets. That makes me feel purposeful and proud.
As I am now being head-butted by Gimli's brother, Bilbo Bombadil, I must cease my ponderings for today and find something for this boy to nosh on.
04 February 2009
GimmiesFishes.org
In the hopes of establishing an official home for Gimmie's Fishes domain and hosting set-up was completed today.
This blog will still be in use but mirrored at the official site.
GimmiesFishes.ORG
This blog will still be in use but mirrored at the official site.
GimmiesFishes.ORG
31 January 2009
A new year... a new determination.
January hit the ground running. I'm finding it incredible that the month is almost gone. Seems like 2008 was never-ending... for me... it certainly had a lasting affect.So, the holidays are behind us and the tree is tucked away in its box for another year. Now it's time to roll up the sleeves and get back to work.
Determination can be an odd companion. At times it is never-yeilding; at other times it is ever-wanning. But if it's truly there then deeds can be done.
Determination can be an odd companion. At times it is never-yeilding; at other times it is ever-wanning. But if it's truly there then deeds can be done.
[ photo of Junipurr Lily and Rosie Rosebud, titled "We're Pal's!" ]
I've had a few things impose themselves upon the temporary "retirement" from my cause - and all have been positive.
Back in early December I had an email from a vet that works at the Paris, France corporate office of Royal-Canin.
I doubt anyone is actually following this blog, but if so one might recall that I had attempted to contact a vet at RC for help and was told that she was moving to Brazil and a new vet would be taking over her position. The vet I contacted promised to give my emails and contact information to the new person. Days, then weeks, then months passed and nothing... and then in came an email from the new veterinarian.
She wrote:
C. Galli sent me your e-mail and your request. First of all, I'm sorry for this late answer but it took time to collect some information and because of personnal issues I couldn't send you this e-mail before.
In fact, I haven't found other researchs written by Dr Houard or scientfific research related to ketamine & sphynx. It seems that his paper was the result of his personal experience, as he has a private practice near Paris.
I've searched for people you could contact on this subject: it exists some veterinary associations specialised in anesthesia . They may have observed the same thing as they are specialised in this field and they consult a lot of cats & dogs.
These are the contacts I've found in the USA:
Veterinary analgesia and anesthesia support group http://www.vasg.org/
American college of veterinary anesthesiologists http://www.acva.org/
Hope it will help you, Best regards
S. Rivière
--------------------------------------------------------
I found her email encouraging and it gave a renewal to my quest... if only for the sake of having someone remember and feel it important enough to respond. See? I am so desparate for any success that even the slightest thing is a milestone.
So, then I had not one, but TWO emails sent from Sphynx owners. One in South Africa, and one from the USA. Both had heard that I had documents on Ket/Val and Sphynx and asked if I could provide them literature to give their vets. Which I most happily did. Oh, but to save one life, one heart from breaking. Encouragement!
On 07 January I was contacted by a fellow Sphynx lover who happens to be a very successful breeder as well; Arden Gaitlin-Andrews, of AngelFire Sphynx cattery. She said that she was starting an International Sphynx Breeder/Enthusiast Newsletter - for the SX community - and asked if I would be the Editor of the owner's section.
I jumped at the chance.
Now.. bear in mind I jump at chances regardless of if they have a monetary value to my time. For years I've bashed my head in, locally and w/in my own apathetic community, to bring about a community band, a community dinner-theatre, and a 5-county non-profit arts council. All were successful but back-mind-and-spirit breaking experiences. After resigning as president from the arts council I took a solomn (well other than my rants to exceptionally close friends) oath to NEVER, EVER put myself out for my unappreciative community again.
But this is different. This strikes a cord. This would allow me a platform, a voice, and a way to help countless others know more about the Sphynx breed. It would allow me to share my findings directly with others who are interested.
So.. yeah, well.. you see where this is going. :-)
Our first newsletter - Volumn 1 - will be distributed digitally and will cover the months of March/April 2009. Some of the topics covered are:
- Safram Sphynx - by Sandy Adler
- Nebulization - by Diana Scott & Carolyn McGuire, DVM
- With or Without the Necklace? - by Carlee Marrer-Tising
- Genetics 101 - by Paul Patton
- Bath Time - by Cyndee Gause
- A Special Goodbye [Sue Gleason] - by Paul Patton
- Feline HCM - by Judy Webb Gunby
- Judging Sphynx Across Associations - by Mary Perfitt-Nelson
- Sphynx Multiples - by Kay Marshall
- Showing Sphynx in Switzerland - by Carlee Marrer-Tising
- B.A.R.F. - by Judy Webb Gunby
I would like to encourage you to join our FREE subscription list at Sphynx Newsletter Subscribers Yahoo Groups (mention this blog in your request to join), or you can visit us online at our Sphynx Breeder/Enthusiasts Newsletter Blog and on Facebook.
I do appreciate any readership this blog has. If you are reading it ... thanks.
Artwork copyright of K.Marshall
24 December 2008
A Christmas without our ReinDear...
Gimli... our little precious, sweet, and very irritated reindeer. What a face, and how we miss him!
Gimli loved any events that involved a chance for him to show-off. Christmas and Thanksgiving were major events for our Gims.
This year we had new little friends in our lives -- Junipurr Lily and Rosie Rosebud (Rose of Sharron), and of course our darling Bilbo.
The girls enjoyed every single aspect of the holidays and gave us so many laughs as they experienced one "first" after another.
But through it all there was one missing and one that was missed.
After "the curtain fell" in late October I will admit to having a need for a time-out. A time to regroup and reaffirm. That's OK. I know my resolve will return.
What isn't known by some is how much resolve I actually have.
I'll not forget, Gimli, and I will not allow your death to be in vain.
We love you! Mom & Dad, Bilbo, Lily, and Rose.
Our seasonal card - FRONT
Our seasonal card - INSIDE
Message on Gimmie's photo reads:
In memory of Godz Gimli-GilGalad who was defeated in life by Ketamine and HCM.
Please support the Winn Feline Foundation.
In memory of Godz Gimli-GilGalad who was defeated in life by Ketamine and HCM.
Please support the Winn Feline Foundation.
01 November 2008
And the curtain fell to no applause...
After a moment of joyous rapture in locating Dr. Houard (after a six-month effort), the curtain came crashing down.
I had located him. I prepared a letter of introduction and explanation of why I was reaching out to him. My friend, Mary Perfitt-Nelson, of Enchanted Lair & GoNaked Sphynx, offered to lend me the help of her brother-in-law, Laurent (a Frenchman), who kindly translated my documents into French.
I bundled my two airmail packages up and sent them International Express to both Dr. Houard, in Paris, and his former assistant (now living in Canada), Aline Noel. Mme. Noel took my letter on her next trip to Paris -- the day AFTER my letter arrived -- and personally sat down with Dr. Houard to go over it with him and explain my interest in Ketamine.
How kind and generous people can be... even those whom I have never met.
The last week in October my husband and I, and our Sphynx kids, Bilbo, Lily, and Rose, went RV camping for a week. The day we left and only a few short days after sending my letter to Dr. Houard I received a reply back, via email, from him.
He wrote:
Dear Mme.
I attentively read your mail. I believe that it is necessary to distinguish two phenomena at the time of the first usage of the Kétamine.
Which you eventually observed can relate itself to an intolerance to the dissociative anesthetic, of which the leader is the Kétamine, cats Rex Devon and Sphynx that I evoked in the magazine "Cat Interests Me".
I did not publish this phenomenon in other reviews for I did not succeed explaining the pathégonie of this disturbance.
The death of your cat at the time of the second anesthésie is classical when it exists a cardiomypathie, all anesthetic other probably would have provoked the same consequence. I hope qu these precisions will be useful for you.
Sincere greetings.
Dr Michel HOUARD
I had located him. I prepared a letter of introduction and explanation of why I was reaching out to him. My friend, Mary Perfitt-Nelson, of Enchanted Lair & GoNaked Sphynx, offered to lend me the help of her brother-in-law, Laurent (a Frenchman), who kindly translated my documents into French.
I bundled my two airmail packages up and sent them International Express to both Dr. Houard, in Paris, and his former assistant (now living in Canada), Aline Noel. Mme. Noel took my letter on her next trip to Paris -- the day AFTER my letter arrived -- and personally sat down with Dr. Houard to go over it with him and explain my interest in Ketamine.
How kind and generous people can be... even those whom I have never met.
The last week in October my husband and I, and our Sphynx kids, Bilbo, Lily, and Rose, went RV camping for a week. The day we left and only a few short days after sending my letter to Dr. Houard I received a reply back, via email, from him.
He wrote:
Dear Mme.
I attentively read your mail. I believe that it is necessary to distinguish two phenomena at the time of the first usage of the Kétamine.
Which you eventually observed can relate itself to an intolerance to the dissociative anesthetic, of which the leader is the Kétamine, cats Rex Devon and Sphynx that I evoked in the magazine "Cat Interests Me".
I did not publish this phenomenon in other reviews for I did not succeed explaining the pathégonie of this disturbance.
The death of your cat at the time of the second anesthésie is classical when it exists a cardiomypathie, all anesthetic other probably would have provoked the same consequence. I hope qu these precisions will be useful for you.
Sincere greetings.
Dr Michel HOUARD
---------------------------------------------------------------------------------
I wrote back immediately, that morning, but have not yet received a reply. It is my belief that this kind doctor opened a new email account just to reply to me directly. I am guessing that he has not checked it since.
Dear Dr. Houard,
I wish to thank you for your response to my letter. I am curious of the phenomenon that you talked about in your e-mail and I would like to ask if I can continue to communicate questions that I have in consideration of Ketamine and the cats in the exotic types, notably the Sphynx. You said that it is necessary to distinguish two phenomena when Ketamine is used for the first time. What are the two distinctive identifying phenomena? Is it your opinion that there is a strong connection between the usage of Ketamine and the progression of a myopathy (cardio or hereditary myopathy) in Sphynx and Devons? Pardon me for misunderstanding; but, in your opinion, would any type of anethesia given to a cat with HCM have the same resulting death? Would that apply to HCM cats given isoflurane or sevoflurane or only cats in the exotics line? Other veterinary doctors have posted serious concerns in the matter of Ketamine used on cats with a common genetic link. I would like to provide a document that details a discussion of this subject by American veterinarian, Dr. Mike Richards. Dr. Richards provided answers to AOL members regarding pet-related questions. If doctors know about the potential dangers of Ketamine and other disassociative anesthesias is there not a need for this information to be more available to veterinarians and pet owners? I use a program of translation of language to communicate with you, so please forgive any errors in the syntax and grammar. I wish to again thank you, and Aline, for communicating with me. I am optimistic that a communication line can continue.
---------------------------------------------------------------------------------
The very same day that his email came in to my account the postal service delievered a letter, from the insurance company representing the vet that killed Gimli, stating that they declined my request for replacement, necropsy, creamation, and mileage costs. A total lack of accountability even WITH a statement from the pathologist that the Ketamine caused his death.
The very same day that his email came in to my account the postal service delievered a letter, from the insurance company representing the vet that killed Gimli, stating that they declined my request for replacement, necropsy, creamation, and mileage costs. A total lack of accountability even WITH a statement from the pathologist that the Ketamine caused his death.
Emotions that had subsided through my sense of purpose eroded into tears of frustration, anger, and immense sadness. It was, literally, all I could do to gather my bags and join my husband and our cat-kids in the RV for the trip.
Am I defeated? No... but I am temporarily behind the curtains.
09 September 2008
One more reason why I prefer pets to people...
For the past ten weeks I have been patiently waiting word from a doctor of veterinary cardiology who agreed to phone Dr. Houard, in Paris, France (to try to validate his research, etc.).
I was asked to be patient and, despite my natural personality type (which includes an impatience gene), I have waited with hopeful expectation of an answer or in anticipation of a new direction to scope out.
I phoned the Drs. office late last month and was told I would get a return call. Didn't happen.
I phoned again the end of last week and was told that I could speak with the doctor on Monday. Monday the doctor was out, so I left a message asking if I could have ten minutes of her time today to discuss her efforts in speaking with Dr. Houard or his associates.
... an answering service called to tell me that the doctor had tried to phone Dr. Houard many weeks back, and did not get a reply.
Now.. one might ask; what is my gripe?
-- Did the doctor fulfil her promise to me? hmmmm... well, I suppose so, if pressed for an answer.
-- Did the doctor follow up with me so I would no longer be kept waiting and wondering? That one's easy. No.
-- Do I appreciate the effort, regardless of the lack of compassion shown to my inquiry and concern?
That's tough... well, tough, I should say, for me to be gracious.
Had I received a courteous (dare I say, even conscientious?) update from the doctor I would not be sitting here feeling like my efforts are unimportant, feeling irritated and anxious, and wondering why such a small courtesy could not have been extended. How long ago she tried to phone him? Was it only one, quick effort?
How many days and weeks have passed by that could have been used searching for someone fluent in French to make that call?
I don't have a clue as to the age of the researcher, Dr. Houard. For all I know he may be young and still very active in his field; but what if he is not? What if there is a window of opportunity to find out the questions I need to verify? These are the notions that so worry me.
Yesterday (08 September) marked the fifth month since Gimli was killed through the use of Ket/Val during a routine dental cleaning. Yes... feelings are still raw and, as the days, weeks, and MONTHS push onward I feel an urgency to press forward and make some progress.
In some ways I feel... haunted. I don't mean to imply that in a spiritual sense or a malicious sense... but rather in an obligatorial sense.
I feel indebted to Gimli for the love and joy he brought into our lives.
I feel indebted to him to make his death meaningful and helpful to others.
Therefore.. all of this is pretty important to me. Such are the things that drive people into action.
Do YOU, kind reader, know of someone who might be willing to help? I'm suffering from a locale problem as well... for, unfortunately, in my area French is not taught in our local schools or local community college, nor anywhere within my immediate vicinity.
If so, please contact me through this blog. I could use some good fortune about now.
So in my pondering and silent debate on Pets vs. People, Pets seem to be winning out.
Final thought today: I feel very much alone in this quest to help our breed.
I was asked to be patient and, despite my natural personality type (which includes an impatience gene), I have waited with hopeful expectation of an answer or in anticipation of a new direction to scope out.
I phoned the Drs. office late last month and was told I would get a return call. Didn't happen.
I phoned again the end of last week and was told that I could speak with the doctor on Monday. Monday the doctor was out, so I left a message asking if I could have ten minutes of her time today to discuss her efforts in speaking with Dr. Houard or his associates.
... an answering service called to tell me that the doctor had tried to phone Dr. Houard many weeks back, and did not get a reply.
Now.. one might ask; what is my gripe?
-- Did the doctor fulfil her promise to me? hmmmm... well, I suppose so, if pressed for an answer.
-- Did the doctor follow up with me so I would no longer be kept waiting and wondering? That one's easy. No.
-- Do I appreciate the effort, regardless of the lack of compassion shown to my inquiry and concern?
That's tough... well, tough, I should say, for me to be gracious.
Had I received a courteous (dare I say, even conscientious?) update from the doctor I would not be sitting here feeling like my efforts are unimportant, feeling irritated and anxious, and wondering why such a small courtesy could not have been extended. How long ago she tried to phone him? Was it only one, quick effort?
How many days and weeks have passed by that could have been used searching for someone fluent in French to make that call?
I don't have a clue as to the age of the researcher, Dr. Houard. For all I know he may be young and still very active in his field; but what if he is not? What if there is a window of opportunity to find out the questions I need to verify? These are the notions that so worry me.
Yesterday (08 September) marked the fifth month since Gimli was killed through the use of Ket/Val during a routine dental cleaning. Yes... feelings are still raw and, as the days, weeks, and MONTHS push onward I feel an urgency to press forward and make some progress.
In some ways I feel... haunted. I don't mean to imply that in a spiritual sense or a malicious sense... but rather in an obligatorial sense.
I feel indebted to Gimli for the love and joy he brought into our lives.
I feel indebted to him to make his death meaningful and helpful to others.
Therefore.. all of this is pretty important to me. Such are the things that drive people into action.
Do YOU, kind reader, know of someone who might be willing to help? I'm suffering from a locale problem as well... for, unfortunately, in my area French is not taught in our local schools or local community college, nor anywhere within my immediate vicinity.
If so, please contact me through this blog. I could use some good fortune about now.
So in my pondering and silent debate on Pets vs. People, Pets seem to be winning out.
Final thought today: I feel very much alone in this quest to help our breed.
05 July 2008
Three months and standing still...
I've been thinking so much about the progress I've made and *not* made on this journey that's been forced upon me. To be honest, I've felt guilty for not posting since the 22nd of June. The reason is... I've needed some time away.
I cry at the drop of a hat when I think about Gimli and why he died. I'm still reeling and I feel depressed.
One might think that because Gimli was a "pet" that his life is over and we, I, should now move on. We have two new kittens to "take his place" and Bilbo's trying hard to adjust... we should be OK, right?
Oh how I wish it were so easy.
The girls, Junipurr Lily and Rose, are delightful. They've adjusted well, Bilbo loves them, we adore them, and I'm grateful for them being in our home and our lives... but they are not Gimli. They can't take his place in our hearts and they don't make the hurt and anger go away. I often think how unfair it is to them that I can't be overjoyed that they are with us as I was when we first got the boys. I'm simply not capable of feeling that sort of joy now.
So.. I've taken a break. I have people I need to nudge who have promised to be proactive for me -- or for the cause (Ketamine deaths in our breed). I have people who have reached out to me that I've yet to contact... to my shame. I have let the ball drop these past three weeks; but I've needed a break from the constant sadness, the constant anger, the constant drive and late-nights of research.
I have a new business that's getting off the ground next week... it's a business that I've been trying to grow since 2004 and, for the first time, it really has a chance of being successful. I should be plunging myself head-first into this project with no other thoughts in my head but its groundbreaking debut. I'm trying to do that. I owe it to myself and to my partner who is not an animal lover and can not understand (but, to his credit, has tried).
I'll get past this month and continue anew. My committments include not only my work and new project, but necessary time and trips to doctors with my dad and with our Sphynx kids. The little girls are now five months old and ready to be spayed and microchipped. That process is scheduled for 22 July, and they'll use an Isoflurane box during the process. Still.. I'm dreading it. I dread it for our girls and I dread the way I know I will feel during the process... scared, anxious, and memory-filled. Wish us luck, please.
As for our Gimmie -- I kiss his urn each night and tell him good morning the next day. We miss him, and want his legacy to be filled with potential life-saving information for other Sphynx owners.
Our attorney has been approached by the vet who is responsible for his death. She phoned him to clear her character. I can't imagine her motive in phoning him. Our case is now in the hands of her insurance company, and if things don't work out well there I have full intention of seeing it through in court. She will be held accountable.
I appreciate those who read this blog. I encourage you to view the posts from May which detail the Ketamine findings. Please don't leave this blog without viewing the information there.
PHOTO: Our sweet boy, Gimli, riding in his "going home" spot in our motorhome. We've not camped since we lost our boy.
I cry at the drop of a hat when I think about Gimli and why he died. I'm still reeling and I feel depressed.
One might think that because Gimli was a "pet" that his life is over and we, I, should now move on. We have two new kittens to "take his place" and Bilbo's trying hard to adjust... we should be OK, right?
Oh how I wish it were so easy.
The girls, Junipurr Lily and Rose, are delightful. They've adjusted well, Bilbo loves them, we adore them, and I'm grateful for them being in our home and our lives... but they are not Gimli. They can't take his place in our hearts and they don't make the hurt and anger go away. I often think how unfair it is to them that I can't be overjoyed that they are with us as I was when we first got the boys. I'm simply not capable of feeling that sort of joy now.
So.. I've taken a break. I have people I need to nudge who have promised to be proactive for me -- or for the cause (Ketamine deaths in our breed). I have people who have reached out to me that I've yet to contact... to my shame. I have let the ball drop these past three weeks; but I've needed a break from the constant sadness, the constant anger, the constant drive and late-nights of research.
I have a new business that's getting off the ground next week... it's a business that I've been trying to grow since 2004 and, for the first time, it really has a chance of being successful. I should be plunging myself head-first into this project with no other thoughts in my head but its groundbreaking debut. I'm trying to do that. I owe it to myself and to my partner who is not an animal lover and can not understand (but, to his credit, has tried).
I'll get past this month and continue anew. My committments include not only my work and new project, but necessary time and trips to doctors with my dad and with our Sphynx kids. The little girls are now five months old and ready to be spayed and microchipped. That process is scheduled for 22 July, and they'll use an Isoflurane box during the process. Still.. I'm dreading it. I dread it for our girls and I dread the way I know I will feel during the process... scared, anxious, and memory-filled. Wish us luck, please.
As for our Gimmie -- I kiss his urn each night and tell him good morning the next day. We miss him, and want his legacy to be filled with potential life-saving information for other Sphynx owners.
Our attorney has been approached by the vet who is responsible for his death. She phoned him to clear her character. I can't imagine her motive in phoning him. Our case is now in the hands of her insurance company, and if things don't work out well there I have full intention of seeing it through in court. She will be held accountable.
I appreciate those who read this blog. I encourage you to view the posts from May which detail the Ketamine findings. Please don't leave this blog without viewing the information there.
PHOTO: Our sweet boy, Gimli, riding in his "going home" spot in our motorhome. We've not camped since we lost our boy.
14 June 2008
When the heart gets discouraged Fate often intervenes
I've been in what's typically called a "funk" today. As I told a friend of mine, I believe it's a combination of things that includes my sadness for Gimli's loss - and yes, we still miss him terribly - my being behind in my job due to this constant and never-ending distraction, and what seems like a wanning of interest (it's been two months, time to move on, right?).
Not that simple - can't move on; I'm stuck, you see. Even with the enrichment of our two new little Sphynx girls - Lily and Rose - there is a pervasive need (compulsion) to push on in this quest for validation of the Ketamine (or Ket/Val) link with deaths in our breed. I can't stand to think of another family going through the misery we are due to vets being unaware or, uncaring.
and then...
Later this evening I had an email that came in from our breeder (grandmother to our kittens, Bilbo and Gimli) that she kindly forwarded to me. A vet she knows from somewhere in the world (I don't know specifics yet) wrote to her about finding this blog (I'm glad you did!).
She wrote, in part:
"Would you please let his owners know that I am so sorry and that there are veterinary professionals out there who know about the risks involved with ketamine in cats. Our clinic does not give ketamine (or drugs like Telazol with tiletamine) in cats for induction of anesthesia, period. Any breeds. I also read their frustration about not being able to get access to VIN (Veterinary Information Network). I am a member and I cannot give out my login information but I am more than happy to save and send them copies of all the info I can find on the subject.
I spoke to Dr. _____, our medical director & practice owner, about Gimli and she asked me to send her a link to the blog so she can formulate an informative and compassionate response. She wants to help spread the word and be an ally to the rex cat community. If Gimli's people would like to email me, let them know they can. I can't imagine the pain they feel right now but it might help to know there are some of us out there advocating for these little guys and who have adjusted their protocols to provide the very best possible care available. Because as they said, a cat is not just a cat and it's high time *some* vets (not all, because there are a lot of great ones out there) stop performing these 'cookbook' recipe sedations for *routine* procedures. No procedure is routine in the first place. There is always a risk and owners should be informed. It makes me sick they told them there was no alternative."
I can't adequately describe how uplifting this email was for me tonight. I cried when I read it - tears of gratitude for the kindness of strangers, and for the hope that this new "door" may open up more avenues to continue this quest for confirmation on Dr. Houard's article, and on the link between Ket/Val related deaths in our breeds. What this all may ultimately do is save countless felines from death or the advancement of HCM, and save countless pet owners the heartbreak of loss through ignorance or ethical research done on behalf of their patients.
One particular thing that struck me was that this vet's medical director wanted to send us condolences. Neither of these people know us or Gimmie - but they *care*.
We have NEVER YET received any personal note of sympathy or apology from the vet who caused Gimli's death - not one single, solitary word. Of course, we - and many who know us and our story - believe that act alone depicts guilt.
As an aside to this wonderful news I had another email yesterday from a Sphynx owner who had a scheduled dental cleaning for her Sphynx. She printed out the information here and presented it to her vet (who was planning on using Ketamine) and due to that they have opted for the Isoflurane gas as an option. News like that is so bittersweet (although that is selfish to admit). I can't help but wish that someone could have warned ME about it before Gimli had to die.
Really... he was just the most wonderful and marvelous little thing. I wish I could describe him better. He was special, and he is most sincerely missed.
Not that simple - can't move on; I'm stuck, you see. Even with the enrichment of our two new little Sphynx girls - Lily and Rose - there is a pervasive need (compulsion) to push on in this quest for validation of the Ketamine (or Ket/Val) link with deaths in our breed. I can't stand to think of another family going through the misery we are due to vets being unaware or, uncaring.
and then...
Later this evening I had an email that came in from our breeder (grandmother to our kittens, Bilbo and Gimli) that she kindly forwarded to me. A vet she knows from somewhere in the world (I don't know specifics yet) wrote to her about finding this blog (I'm glad you did!).
She wrote, in part:
"Would you please let his owners know that I am so sorry and that there are veterinary professionals out there who know about the risks involved with ketamine in cats. Our clinic does not give ketamine (or drugs like Telazol with tiletamine) in cats for induction of anesthesia, period. Any breeds. I also read their frustration about not being able to get access to VIN (Veterinary Information Network). I am a member and I cannot give out my login information but I am more than happy to save and send them copies of all the info I can find on the subject.
I spoke to Dr. _____, our medical director & practice owner, about Gimli and she asked me to send her a link to the blog so she can formulate an informative and compassionate response. She wants to help spread the word and be an ally to the rex cat community. If Gimli's people would like to email me, let them know they can. I can't imagine the pain they feel right now but it might help to know there are some of us out there advocating for these little guys and who have adjusted their protocols to provide the very best possible care available. Because as they said, a cat is not just a cat and it's high time *some* vets (not all, because there are a lot of great ones out there) stop performing these 'cookbook' recipe sedations for *routine* procedures. No procedure is routine in the first place. There is always a risk and owners should be informed. It makes me sick they told them there was no alternative."
I can't adequately describe how uplifting this email was for me tonight. I cried when I read it - tears of gratitude for the kindness of strangers, and for the hope that this new "door" may open up more avenues to continue this quest for confirmation on Dr. Houard's article, and on the link between Ket/Val related deaths in our breeds. What this all may ultimately do is save countless felines from death or the advancement of HCM, and save countless pet owners the heartbreak of loss through ignorance or ethical research done on behalf of their patients.
One particular thing that struck me was that this vet's medical director wanted to send us condolences. Neither of these people know us or Gimmie - but they *care*.
We have NEVER YET received any personal note of sympathy or apology from the vet who caused Gimli's death - not one single, solitary word. Of course, we - and many who know us and our story - believe that act alone depicts guilt.
As an aside to this wonderful news I had another email yesterday from a Sphynx owner who had a scheduled dental cleaning for her Sphynx. She printed out the information here and presented it to her vet (who was planning on using Ketamine) and due to that they have opted for the Isoflurane gas as an option. News like that is so bittersweet (although that is selfish to admit). I can't help but wish that someone could have warned ME about it before Gimli had to die.
Really... he was just the most wonderful and marvelous little thing. I wish I could describe him better. He was special, and he is most sincerely missed.
04 June 2008
These video's would have been longer had we known his life would be cut short
Some videos of Gimli taken in February.
If this boy *did* have HCM there were, absolutely, no signs. Especially telling since his heart - at death - weighed 28 grams. Even yet, the pathologist agreed that Ketamine ended his life on 08 April, not a "possible" disease. Was Gimmie's heart tested unequivocally for HCM... No.
The only thing certain was that Gimli went into CHF after being given Ketamine. Everything else is speculative.
I hate the last video is sideways. I'm primarily a still photographer and took these videos from my digital camera. I'd flipped the camera sideways - as I normally to - and completely forgot that I'd have trouble with it later. Just turn your heads for now...
I did just order a Canon PIXIA high definition camcorder. My husband and I do not want to miss anything with Bilbo and the girls. I have real regrets over not having more video of Gimmie... I just never expected his life would be over before we made this planned purchase for our anniversary gift. Twelve years on 18 June. :-)
If this boy *did* have HCM there were, absolutely, no signs. Especially telling since his heart - at death - weighed 28 grams. Even yet, the pathologist agreed that Ketamine ended his life on 08 April, not a "possible" disease. Was Gimmie's heart tested unequivocally for HCM... No.
The only thing certain was that Gimli went into CHF after being given Ketamine. Everything else is speculative.
I hate the last video is sideways. I'm primarily a still photographer and took these videos from my digital camera. I'd flipped the camera sideways - as I normally to - and completely forgot that I'd have trouble with it later. Just turn your heads for now...
I did just order a Canon PIXIA high definition camcorder. My husband and I do not want to miss anything with Bilbo and the girls. I have real regrets over not having more video of Gimmie... I just never expected his life would be over before we made this planned purchase for our anniversary gift. Twelve years on 18 June. :-)
02 June 2008
News from the WINN Foundations HCM / DNA research
Posted to Sphynx Breeders list:
Molecular evaluation of the feline myosin heavy chain gene in Ragdoll, Norwegian Forest and Sphynx cats with familial hypertrophic cardiomyopathy
12 Month Progress Report - 2007
Principal Investigator: Kathryn M. Meurs, DVM, Ph.D.
Diplomate ACVIM (Cardiology)
Professor - Dept of Veterinary Clinical Sciences
Washington State University-College of VeterinaryMedicine
Pullman, WA 99164
Phone: 509-335-0817
Email: meurs@vetmed.wsu.edu
Hypothesis: A mutation in the exonic or splice siteregion of the myosin heavy chain gene is responsible for familial hypertrophic cardiomyopathy in the Ragdoll, Sphynx or Norwegian Forest cat.
Objective of the Study: To evaluate the exonic andexonic/intronic splice site regions of the myosin heavy chain gene in Ragdoll, Sphynx and NorwegianForest cats with familial hypertrophic cardiomyopathyby PCR based sequencing.
Results: Although myosin heavy chain gene is the most commonly mutated gene in human beings, we did not find a causative mutation for hypertrophic cardiomyopathy in any of these breeds. We did identify several single nucleotide polymorphisms (SNPs) that are base pair changes that are shown NOT to be responsible for the disease since they do not segregate only with the affected cats, do not change the amino acid or do not appear to change the protein produced.
Although the MYH7 gene does not appear to be causative for hypertrophic cardiomyopathy in these breeds, we have continued the study by starting to evaluate additionalgenes known to cause the disease in people.
Additionally, we have submitted an abstract for presentation on this work at the American College of Veterinary Internal Medicine meeting in San Antonio,Texas in June 2008 and we have started a publication on this work that should be submitted within the next 4-8 weeks.
Read more & Visit the WINN Foundation website
Molecular evaluation of the feline myosin heavy chain gene in Ragdoll, Norwegian Forest and Sphynx cats with familial hypertrophic cardiomyopathy
12 Month Progress Report - 2007
Principal Investigator: Kathryn M. Meurs, DVM, Ph.D.
Diplomate ACVIM (Cardiology)
Professor - Dept of Veterinary Clinical Sciences
Washington State University-College of VeterinaryMedicine
Pullman, WA 99164
Phone: 509-335-0817
Email: meurs@vetmed.wsu.edu
Hypothesis: A mutation in the exonic or splice siteregion of the myosin heavy chain gene is responsible for familial hypertrophic cardiomyopathy in the Ragdoll, Sphynx or Norwegian Forest cat.
Objective of the Study: To evaluate the exonic andexonic/intronic splice site regions of the myosin heavy chain gene in Ragdoll, Sphynx and NorwegianForest cats with familial hypertrophic cardiomyopathyby PCR based sequencing.
Results: Although myosin heavy chain gene is the most commonly mutated gene in human beings, we did not find a causative mutation for hypertrophic cardiomyopathy in any of these breeds. We did identify several single nucleotide polymorphisms (SNPs) that are base pair changes that are shown NOT to be responsible for the disease since they do not segregate only with the affected cats, do not change the amino acid or do not appear to change the protein produced.
Although the MYH7 gene does not appear to be causative for hypertrophic cardiomyopathy in these breeds, we have continued the study by starting to evaluate additionalgenes known to cause the disease in people.
Additionally, we have submitted an abstract for presentation on this work at the American College of Veterinary Internal Medicine meeting in San Antonio,Texas in June 2008 and we have started a publication on this work that should be submitted within the next 4-8 weeks.
Read more & Visit the WINN Foundation website
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